Discovery Will Change The Way Researchers Look At DNA Transcription
Posted: Thursday, August 2, 2001
CHAPEL HILL – Biological chemists at the University of North Carolina at Chapel Hill say a discovery they have made about how living organisms convert genetic instructions into action represents a fundamental advance in the understanding of the flow of genetic information.
The UNC scientists have found a previously unknown chemical site on a key enzyme that regulates production of the genetic messenger known as RNA. When the chemical site is occupied, it markedly speeds up the process by which the information contained in DNA, which serves as genetic blueprints, is converted into functions critical for maintaining life.
A report on the discovery appears in the July 27 issue of Cell, a scientific journal. Authors are Dr. Dorothy A. Erie, assistant professor of chemistry; Dr. J. Estelle Foster, a former student of Erie’s now at Eli Lilly and Company, the pharmaceutical manufacturer; and chemistry doctoral student Shannon F. Holmes. More
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